The Center was founded in 1986, following a Presidential Decree (art. 91 of DPR 382/80), by convention between the Universities of Florence, Rome “La Sapienza” and Rome “Tor Vergata” and named “Center for the Study of Molecular Mechanisms involved in Tissue Damage from Hypoxia and Hyperoxia”. The Universities of Ferrara and Aquila began participating in the Center’s activities in 1991. The Center has its administrative and organizational Headquarters at the University of Florence, and it was directed from the beginning until 1996 by its founder, Prof. Alberto Giotti. In 1996, after a unanimous vote by the Council following a proposal of the Director, the Center’s name was changed to “Interuniversity Center of Molecular Medicine and Applied Biophysics” (C.I.M.M.B.A.), following which the Direction passed to Prof. Fabrizio Ledda, to Prof. Alessandro Mugelli and then to the current Director, Prof. Elisabetta Cerbai.
Following a convention with the Department of Preclinical and Clinical Pharmacology, the Center has a laboratory in the Department’s building that is used mainly to host italian and foreign researchers who operate in the scientific and methodological areas of interest of the Center.
In accordance with the Statute of the Center, C.I.M.M.B.A. has the following objectives:
- organize interdisciplinary research in the biomedical field;
- promote the exchange of information and material between the participating institutions;
- collaborate with other University Departments and Institutes and with the National Research Center (CNR);
- promote the exchange of information and material on an international and a national level .
In its present structure, C.I.M.M.B.A. combines the skills of researchers from different sectors such as biochemistry, pharmacology, basic and applied biology, and experimental and clinical medicine. It represents a biomedical research organization characterized as an interdisciplinary network linked to important international research laboratories. The research activity of the operative Units participating in C.I.M.M.B.A. is marked by the use of the most advanced methodologies in the fields of biochemistry, biophysics, molecular biology and image analysis, as well as those which are appropriate for the study of receptor molecular interactions and post-receptor cellular signals.